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Elucidating the pathophysiology of syringomyelia

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This is comparable to a cyst, a cavity filling with a fluid identical of similar to cerebrospinal fluid and extracellular fluid, which slowly expands, putting pressure on the spinal cord and thus damaging it.

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Obstruction of CSF (cerebro-spinal fluid) circulation from the basal posterior fossa to the caudal space may cause syringomyelia of this type.At the moment, no specific Chiari or Syringomyelia scale has been made, but for now, we most often use the KPI: Karnofsky Performance Index Although it is quite a crude measure, it relies on doctor assessment and some research indicates that the scale is not very reliable, we use it until a better suited scale is created and has been tested for validity and reliability.There is no specific medical treatment for syringomyelia, but the origin of the disease can be met.chiari deformation or Arnold Chiari Malformation) .The symptoms identifying this particular disease aren’t always clear.The discomfort, which is sometimes experienced early in the course of the disease, generally is deep and aching and can be severe.

Syrinx extension into the anterior horns of the spinal cord damages motor neurons (lower motor neuron) and causes diffuse muscle atrophy that begins in the hands and progresses proximally to include the forearms and shoulder girdles. Respiratory insufficiency, which usually is related to changes in position, may occur.

Syringomyelia occurs more frequently in men than in women.

The damage to the spinal cord as seen in patients suffering from Syringomyelia is caused by a Syrinx.

Other similar cystic processes can be Hydromyelia, Myelomalacia, Cystic Neoplasms or Glioependymal Cysts.

Syringomyelia can be easily differentiated because of its association with an underlying disorder that is characterized by obstruction of cerebrospinal fluid flow, tethering of the spinal cord, or a spinal tumor .

The most common example is Arnold-Chiari malformation, which is also associated with communicating syringomyelia.